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The Role Of Haematopoietic Stem Cell Transplantation And...

Discuss the role of haematopoietic stem cells in transplantation and curing disease 1. Hematopoietic stem cells Till and McCulloch described the two hallmarks of Haematopoietic stem cells to be long term self-renewal and the ability to differentiate into all various types of specialized blood cells, with one stem cell able to produce around a million mature blood cells after 20 divisions. The differentiation of these stem cells result in committed hemopoitic progenitor cells which give rise to cells from both the myeloid (monocytes, macrophages,neutrophils, basophils,eosinophils, erythrocytes, mega-karyocytes, platelets and dendritic cells) and lymphoid lineage (T-cells and NK-cells). 2. Hematopoietic stem cell transplantation Tissue engineering is a type of regenerative medicine which aims to replace damaged tissue with new tissue able to resume function and repair structure of normal tissue. Hematopoietic stem cell transplantation was the first type of tissue engineering using stem cells. Hematopoitictic stem cells are infused into the host to treat many blood based disorders including cancers, blood diseases and immunodefiencies. There is a standard procedure for the infusion of these cells, however variations in the relationship between donor and recipient and source of hematopoietic stem cells do cause some variability in the process. 3. Donor/host relationship There are three distinct forms of donor/host relationships involved in HSCT, autologous, allogenic andShow MoreRelatedEssay on Stem Cell Research: Scientific Advancement vs. Human Rights2939 Words   |  12 PagesIntroduction to Stem Cells As improvements in scientific technology and techniques allow for better observations and insights into the natural world, so to do advancements in medical research occur on a seemingly daily basis. On such research topic that has found itself the center of a global debate is the issue of stem cell research. Hailed by some as one of the most dynamic areas of research ever to exist, it is thought to be the next big â€Å"revolution† in medicine, surpassing even the advent

Tourism Hospitality Management Strategies †Myassignmenthelp.Com

Question: Discuss About The Tourism And Hospitality Management Strategies? Answer: Introduction In this age of development and advancement, competition exists right from educational institutions to the business organizations. It is very important to have proper planning for any kind of endeavors regarding both career and business to be competitive in all prospects of career a career cannot be regarded as a job, it is an endeavor that sustains for entire lifetime along with compromising attitudes, feelings and behaviors in a growing process that is oriented by the life goals and work people and moderated by the business organizations they work in. Hence, the development of a good career can be considered as a complex as well as the long-term process which is basically influenced by those sociological, physical, psychological, educational, fortuitous, environmental and economic factors which converge for shaping it in the lifetime of a person. Hence, it is very important for having a proper plan for a career with a strategic approach so as to have a very bright professional caree r endeavors (Buhalis Crotts, 2013). In accordance with the present status of career, I am pursuing my Master's Degree in Business Administration. I am pursuing specialization in the Human Resource and Finances. Getting knowledge about business administration and management are very much beneficial for the career of an individual. I was interested in getting the Masters in Business Administration as enrolling in this course, provides training regarding the practicality and realistic aspects of a business environment. After the completion of the course of MBA, I would find myself as a working professional in the renowned business organizations in the human resource department which I would prefer as my working profile. Throughout the MBA course, I would get the opportunity to have internship and study tour in many renowned business organizations which would provide me with practical knowledge and experience regarding various aspects of business administration (Bunakov et al., 2015). This would also provide me with in-dep th knowledge and information regarding critical issues and challenges that are faced by the human resource managers. I would also get the opportunity to have frequent field visits to many domestic business organizations which will help me regularly in being informed regarding the alterations in the financial aspects. In most of the cases, the companies in which the MBA students are provided the opportunity for having internships provide them with sponsorships regarding their course provided that these students need to be loyal to the company after the completion of their studies. In the second-year of MBA degree, campus placements will be coming for recruitment by various multinational companies for Brisbane location which would provide me with a vital opportunity to be placed in renowned business organizations as an HR professional (Brown, Arendt Bosselman, 2014). Completion of the MBA degree course will also result in a high pay package as the knowledge of this subject is very crucial for any business organization to develop and grow and being an MBA student with relevant knowledge would make me a very preferred candidate for the job profiles. After the working for 1 to 2 years in the multinational company, I would have gained experience to shift to any better multinational company for a highe r professional profile and role which would enhance my abilities and knowledge in the respective field. After gaining experience in the higher level of the field, I can even plan and strategize about my own business ventures and enterprises. In the context of the definition of career, it can be referred to as a series of extremely structured and associated programs of education and the services for assistance which enable the students to have higher levels of jobs in future. Choosing MBA as a major part of career pathway is very much relevant to the definition as this particular Masters Degree provides better scopes and opportunities for having a bright future for me. In regards to the management of career, in the case of my perseverance of the MBA course definitely involves planning regarding the engagements and activities which would provide optimum outcomes regarding future career prospects which would provide me with better fulfillment, financial stability, and growth. Success in any career can be determined by the progress that an individual has made in terms of knowledge, financial stability, and overall fulfillment (Dredge, Airey Gross, 2014). These aspects are definitely obtained by an individual who happens to have their job profile on the basis of an effective MBA degree from any renowned institution or University. I would like to join as a Human Resource Manager in mostly the retail industry which would provide me better scope for dealing with human resource and the financial aspects of ever changing business organizations. I am also interested in joining the companies belonging to the Food and Beverages industries. I would like to work in the HR department of the leading retail companies like Walmart, Tesco, and Aldi across any location in Brisbane. I would appreciate the opportunity to work and supervise the HR department in Coco Cola or PepsiCo. Goal setting The setting of goals both short and long-term is very crucial for having success in the career or any kind of job that an individual is in. It is a fact that setting up goals is a daunting task when it comes to realistic approach. By integrating the Goal setting theory of motivation which integrates the SMART approach can assist in setting effective short-term and long term goals that would direct my career prospect in the orientation of positive and bright future (Gu, 2014). In accordance to the SMART Goal Setting Theory, my goals will be in the orientation of working harder, towards a focused target of education and career. Having specific goals would also help me in assessing my own progress. According to the SMART model, my short-term and long-term goals should be as follows: S-Specific goals need to set so as to have high performance in my studies and overall career. Having specific goals would motivate me to work harder and give my best to my studies along with every aspect of my career. This would provide me with a focused target regarding achieving certain grades. This would also help me in assessing my own progress (Kozak Kozak, 2016). M-Measurable assessment of the goals will help in identifying what I want to learn, achieve and work on various aspects throughout my MBA degree and course. It will help me in breaking down my overall goals into more refined way regarding what exactly I want to manifest physically in regards to my goals and objectives to make it clearer and categorized to be achieved (Ozgit Caglar, 2015). A-Attainable goals in the context of my MBA course and future career prospects will help me in investigating whether my objectives and goals are relevant and achievable according to the current situations. I shall be able to assess my time, effort, and other determinants for achieving both my short and long term goals that will be determined by the priorities and other obligations of my life. I will be able to reach to a particular standpoint even when the circumstances will not be favorable in regards to my MBA career (Kozak et al., 2014). R- Realistic approach to setting up my goal would help me in getting the real and practical perspective of the goals that I would be making in orientation to my MBA course study and the future endeavors based on it. It will not necessarily shorten my bigger dreams but would simply add a realistic view to them (Rahimi et al., 2017). T-Time bound approach to my goals will help me in structuring the efforts and work that is needed to be put for achieving my short and long term goals within a specific time frame. It would help me in deciding the time taken for achieving individual goals as well as overall goals (Leung et al., 2013). Learning Goals The five most important learning or career goals that I wish to achieve within the time frame of 10 years are stated as follows: To be placed in a renowned Multinational company in the job profile of HR Professional for 2 years. To switch the company after gaining relevant experience in the department of human resource in the previous business organization and getting placed in the Managerial roles in the Human Resource Department in a different business organization with the different business organization for next 3 years (Law, Buhalis Cobanoglu, 2014). After having a working experience in leading multinational companies in Brisbane, I wish to begin my own start up regarding food delivery services which would be serving multi cuisines to people. I wish to successfully establish my food delivery service business within 2 years of time frame and then proceed to provide franchise to other entrepreneurs. I wish to begin my own line of business under one umbrella which would have cosmetics and apparels as product lines within the time frame of 10 years. Conclusion Having an effective plan for career is very much necessary to keep achieving success in the any sector of work. One needs to reorient his or her values and goals and make proper preparations to achieve high success rate in their career and business. Refinement, implementation and regulating of the plans and strategies regarding the development of career need to be done on regular basis to ensure overall success. References Buhalis, D. and Crotts, J., 2013. Global alliances in tourism and hospitality management. Routledge. Bunakov, O.A., Zaitseva, N.A., Larionova, A.A., Chudnovskiy, A.D., Zhukova, M.A. and Zhukov, V.A., 2015. Research on the evolution of management concepts of sustainable tourism and hospitality development in the regions. Journal of Sustainable Development, 8(6), p.39. Brown, E.A., Arendt, S.W. and Bosselman, R.H., 2014. Hospitality management graduates perceptions of career factor importance and career factor experience. International Journal of Hospitality Management, 37, pp.58-67. Dredge, D., Airey, D. and Gross, M.J. eds., 2014. The routledge handbook of tourism and hospitality education. Routledge. Gu, Z., 2014. Management Science Applications in Tourism and Hospitality. Routledge. Kozak, M. and Kozak, N. eds., 2016.Tourism and Hospitality Management. Emerald Group Publishing. Kozak, M., Kozak, M., Baloglu, S., Schlter, R.G., Mehmetoglu, M., OMahony, B., Lubbe, B., Huan, T.C., Beaman, J., Cohen, E. and Isin, H., 2014.AnatoliaAn International Journal of Tourism and Hospitality Research. Leung, D., Law, R., Van Hoof, H. and Buhalis, D., 2013. Social media in tourism and hospitality: A literature review. Journal of Travel Tourism Marketing, 30(1-2), pp.3-22. Law, R., Buhalis, D. and Cobanoglu, C., 2014. Progress on information and communication technologies in hospitality and tourism. International Journal of Contemporary Hospitality Management, 26(5), pp.727-750. Rahimi, R., Kseoglu, M.A., Ersoy, A.B. and Okumus, F., 2017. Customer relationship management research in tourism and hospitality: a state-of-the-art. Tourism Review, 72(2). Ozgit, H. and Caglar, M., 2015.The Effectiveness of the Tourism and Hospitality Management Programmes in the Professional Careers of Their Graduates in North Cyprus.Anthropologist, 22(2), pp.397-404.

Marketing and Pick N Pay free essay sample

This marketing plan will be focusing on re-gaining the lost market share and a way to make the company a more profitable organisation without destroying the key aspects of the company. The challenge: Pick n Pay’s offer to the customer focuses on groceries but also goes on to providing other products to their customers such as: clothing, general merchandise, but also includes additional value-added services to cater for Pick n Pay’s customer’s and their evolving needs. Situation Analysis: In 1967 Raymond Ackerman purchased four small stores, launching Pick n Pay as South Africa’s first food discounter. The key aspect of the company is a quintessential family store focused on the customer. Since then Ackerman’s vision has grown and now has expanded to further countries such as: Zambia, Mozambique, Mauritius, Swaziland and Lesotho. Company Analysis: Due to the fact that Pick n Pay is a quintessential family store, Pick n Pay strives to address socio-economic changes through the supply of high-quality, affordable food for all customers, while providing significant employment and economic opportunities for all. The growth and success of Pick n Pay goes down to the following principals: â€Å"Consumer sovereignty; Doing good is good business; and maximising business efficiency. † Mission: â€Å"We serve with our hearts, we create a great place to be with our minds, we create an excellent place to shop. † Values: â€Å"We are passionate about our customers and will fight for their rights. We care for and respect each other. We foster personal growth and opportunity. We nurture leadership and vision, and reward innovation. We live by honesty and integrity. We support and participate in our communities. We take individual responsibility. We are all accountable. † Customer Analysis: Pick n Pay caters to all the markets of South Africa. There is no specific age to shop at Pick n Pay however the age of people who mostly shop at Pick n Pay are aged 18- 65+. There is no specific gender that shop either. This means that in order to achieve a successful marketing strategy Pick n Pay will have to produce an advertisement that will be recognised throughout all the ages and appeal to both sexes. Competitor Analysis: Pick n Pays competitors are Woolworths, Shoprite Checkers and Spar. Although originally Woolworths was the only food store that catered to the ‘upper market’ in South Africa this has changed over the years. Now, Pick n Pay is aiming to supply food to all the target markets and to become the most successful food supplier. Shoprite Checkers is Pick n Pays biggest competitor as both companies have the same vision in becoming the most successful food supplier. Pick n Pay had originally been the first of the two to have established a store to cater to all the markets, but now Shoprite Checkers have started a campaign to appeal to all the markets in re-branding and creating a new image just as Pick n Pay had originally done. Spar caters to the ‘lower income’ market and has the reputation of being the cheapest store to shop from because of the massive amount of poverty in South Africa. SWOT Analysis: Strengths: Fair pricing gives Pick n Pay a cost advantage against competitors. The growth in the use of online markets. Strong band principals giving Pick n Pay a good reputation. Having a supply chain allows the company to grow. Having mini stores to cater for the customers daily basic needs. Weaknesses: Bad communication between customers and Pick n Pay as well as the internal structure of Pick n Pay. Inconsistent product care. Incompetent staff that are not motivated staff who are not motivated to being ambassadors in establishing the company’s fundamental principals. Opportunities: To invest in emerging markets. Expanding the company abroad. To expand on Pick n Pays products and services. Threats: The ever-going competition of competing stores. The economic slowdown will affect the amount of liquidity and the amount that customers will purchase. Competitors could have lower costs to products making Pick n Pays consumers choose to go elsewhere. Product substitution could entail Pick n Pay not producing high quality goods making customers find better value for money shops. Competitors penetrating the market with better global ties and cheaper imported goods. Marketing Segmentation Primary Research: Pick n Pay must get involved in developing communities and giving them the opportunity to have a chance to succeed in South Africa’s economy. This will help the image of Pick n Pay as it will show the customers that when they shop with Pick n Pay that they will initially be helping their community. Secondary Research: To create cheap, re-usable or alternative plastic bags instead of the typical plastic bag. This initiative will allow environmentally friendly people to shop at Pick n Pay as it will show them that Pick n Pay is aware of the environment and that they want to have an eco-friendly community. The bags will be fairly priced and should have a rewards system on the number of bags you buy the more points you will win. Tertiary Research: To make a shopping ‘credit card’ that will allow customers to shop at Pick n Pay without the stress of not having enough liquidity so that they can pay it back when they have enough money, however there should be a limit as to how much someone can spend so that is doesn’t eat into the companies profitability. There should also be a points system on the card that if you pay your account on time and spend over a certain amount you get points and eventually when you have enough points you can either get a discount or an amount off your shopping trip.